Emotions and mental functioning are influenced by a network of interconnected structures in the brain that make up what is known as the limbic system. They play a powerful role in tuning our perception, informing our experience, guiding our decisions and shaping our actions. How they contribute to anxiety, fear, depression, addiction, post-traumatic stress disorder (PTSD), obsessions and compulsions can be understood along dimensions of brain circuit function as it relates to emotion, motivation and affects regulation.
Using neuroscience measures and methods to study the emotional brain and how it evolves over a lifespan and fluctuates with stress, researchers at The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center combine readouts in the laboratory with psychopharmacology, neuromodulation and intervention trials to assess and improve brain circuit function.
Through an increased understanding of the disordered physiological processes inherent in nervous systems with abnormal mental states, they can innovate strategies to prevent the progression of mental illness and treat more patients better and faster and keep them well for longer periods of time.