50 Most Influential Clinical Executives - 2023

Cacchione has overseen the 18-hospital system and research university since 2022. Shortly after he took the lead role, the organization announced it would be restructuring into three regions, down from its previous five divisions, with an eye toward streamlining operations. Cacchione has spoken about the need for the industry to adopt more flexible staffing models, noting that the system has focused on increasing enrollment in its nursing school and that it retained the majority of nurse graduates as employees last year. He came to Jefferson from Ascension Health, where he was executive vice president of clinical and network services.