Commitment of an organization's executive management to information systems as a strategic asset is the single most important determinant of an information systems department's successful function.
Value of strategic initiatives should be subject to a justification process that considers the likely contributions to organizational strategic goals and evidence of value demonstrated in other organizations.
Chief information officers must be involved from the outset in planning for organizational change to allow them to position information systems to facilitate integration processes.
Information systems' organizational structure should mirror overall organizational processes, which in turn should support integration across an organization's functional, clinical and geographic settings.
Leading organizations tend to concentrate effective governance among small groups of senior management, sometimes almost entirely with the CIO. (The latter is not a model for everyone.)
Source: First Consulting Group