The man who drove a cab to put himself through pharmacy school founded U.S. Healthcare in 1975, which became one of the nation's most profitable HMOs. He used strict cost controls as chairman and CEO to capitalize on employers' demands for an end to healthcare inflation in the 1980s. Abramson then went on to make $929 million off a 1996 sale of his company to Aetna for $8.9 billion—almost three times its value. In 1997, the Abramson family donated $100 million to establish the Abramson Family Cancer Research Institute of the University of Pennsylvania. They made another donation of $25.5 million in 2010. Abramson currently is an honorary trustee for the Brookings Institution and consultant and member of the boards of directors of Children's Hospital of Philadelphia and Johns Hopkins University.